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Incorporating ZnFe2O4 nanoparticles and β-cyclodextrin into carbon paste electrode as a sensitive methyldopa electrochemical sensor | ||
Advances in Nanochemistry | ||
دوره 3، شماره 1، آذر 2021، صفحه 10-15 اصل مقاله (1.33 M) | ||
نوع مقاله: Original Article | ||
شناسه دیجیتال (DOI): 10.22126/anc.2021.6533.1025 | ||
نویسندگان | ||
Bahman Mohammadian Asiabar* 1؛ Mohammad Ali Karimi* 1؛ Hossein Tavallali1؛ Mahdi Gholampour2؛ Seied Isa Karanian2؛ Hasan Tavakoli2 | ||
1Department of Chemistry, Payame Noor University, 19395-4697 Tehran, Iran | ||
2Department of Physics and Chemistry, Faculty of Basic Sciences, Imam Ali Military University, Tehran, Iran | ||
چکیده | ||
A new electrochemical sensor for antihypertensive drug methyldopa (MDop) was prepared from a carbon paste electrode modified by hydrothermally synthesized ZnFe2O4 nanoparticles and β-cyclodextrin as a supermolecule. ZnFe2O4 nanoparticles were charectrized using scanning electron microscopy (SEM) and infrared spectroscopy. Comparison of unmodified electrode with electrodes modified by ZnFe2O4 and β-cyclodextrin and their nanocomposite showed that MDop had a higher oxidation current at the modified electrode by composite than each other electrodes at pH = 7. Moreover, the oxidation potential is lower than other electrodes at this pH. The modified electrode can measure MDop in the concentration range of 1-100 μM with a detection limit of 0.3 μM. The proposed sensor shows good repeatability and selectivity. It is also able to measure MDop in the blood serum sample. | ||
کلیدواژهها | ||
Methyldopa؛ ZnFe2O4 nanoparticles؛ β- cyclodextrin؛ Electrochemical sensor | ||
آمار تعداد مشاهده مقاله: 170 تعداد دریافت فایل اصل مقاله: 197 |